Anti-obesity Drug for Dogs

The structure of dirlotapide, from PubChem.

The U.S. Food and Drug Administration just approved Slentrol (dirlotapide), a drug intended to treat obesity in dogs. Roxanne Khamsi of New Scientist writes

A drug specifically designed to treat canine obesity has been approved for the first time by the US Food and Drug Administration.

The drug’s developer, New York-based Pfizer, says the prescription medication will slim dogs, thereby reducing their risk of diseases such as arthritis and cancer. But veterinarians stress that any weight-loss programme for pets must also include lots of exercise and restricted food intake.

(continue reading at New Scientist)

According to the article, 5% of dogs in the United States are obese; apparently, humans’ unhealthful lifestyles are starting to affect our best friend as well—dogs are getting more snacks and less exercise.

Though its mechanism of action is not precisely known, dirlotapide appears to reduce appetite and fat absorption. It’s a liquid given directly to a dog or put in his food.

And no, it’s not approved for human use.