Anti-obesity Drug for Dogs


The structure of dirlotapide, from PubChem.

The U.S. Food and Drug Administration just approved Slentrol (dirlotapide), a drug intended to treat obesity in dogs. Roxanne Khamsi of New Scientist writes

A drug specifically designed to treat canine obesity has been approved for the first time by the US Food and Drug Administration.

The drug’s developer, New York-based Pfizer, says the prescription medication will slim dogs, thereby reducing their risk of diseases such as arthritis and cancer. But veterinarians stress that any weight-loss programme for pets must also include lots of exercise and restricted food intake.

(continue reading at New Scientist)

According to the article, 5% of dogs in the United States are obese; apparently, humans’ unhealthful lifestyles are starting to affect our best friend as well—dogs are getting more snacks and less exercise.

Though its mechanism of action is not precisely known, dirlotapide appears to reduce appetite and fat absorption. It’s a liquid given directly to a dog or put in his food.

And no, it’s not approved for human use.

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7 thoughts on “Anti-obesity Drug for Dogs

  1. LOL re not available for human use.

    Anyway, what a world! In the past, an anti-obesity drug for a dog would have not only been inconceivable; it would have been downright insane.

  2. It seems that people would rather fix the small problems then the bigger ones… (Though I do like the idea for the dogs)

    There should be an increase in convincing people that their size can affect their health and more should be done the diet-pill research.

  3. I agree that this approach is certainly not optimal. Everyone wants a quick fix. I think that people know that their size affects their health; they are just unwilling/unable to do anything about it. You have to remember, too, that humans and dogs evolved in an energy-scarce world. We’ve evolved to enjoy eating, and especially to crave the taste of energy dense foods (fats provide approximately 9 kilocalories per gram, more than twice that of carbohydrates or proteins). And we’ve evolved digestive systems that efficiently break down the food we eat and absorb as much energy and raw materials as possible. A small portion of the human population has developed such ability to make food so easily available that we are faced with an overabundance of high-calorie foods—and that is a situation which we really have no mechanism to deal with. Our ancestors did not face such problems. Our bodies happily grab as much energy as possible and save it for the famine that never comes.

  4. I’ve got an idea. Stop feeding your dog so much food. Stop feeding your cat so much food. Everybody stop eating so much food. Good God, what is wrong with people these days?

  5. Start eating healthier foods and leave the chemicals out of your diet and you will start feeling better and won’t need to eat so much. People just don’t get it. Now they’re pushing drugs to dogs. Shame, shame, shame!!!!!!!!

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